Experimental Neuroinflammation Laboratory
INVESTIGATING INFLAMMATION IN THE BRAIN
Neuroinflammation refers to the inflammatory response within the brain. Our main research focus is to investigate the role of neuroinflammation in the diseased and healthy brain.
Microglia are the major immune cells in the brain. Therefore, the majority of our projects aim to explore the function of these cells and to determine how they contribute to health and disease. In addition, we investigate how lifestyle-related factors, such as physical inactivity and stress, affect neuroinflammation and contribute to brain pathology.
Our research ranges from utilizing experimental models, such as in vitro microglia and in vivo mouse models, to conducting epidemiological investigations on the Swedish population. We combine traditional immunohistochemistry, ELISA, western blot, and animal behavioral tests with novel methods such as transcriptomics, proteomics, bioinformatics, and infrared spectroscopy.
News
Galectin-3 shapes microglial function – possible target in Alzheimer’s disease
Microglia govern the brain and protect it, but in the wrong context, they can also cause harm. Their activity needs to be well timed and balanced, or things go off course. When th...
Nailed it: why do the Swedes nail their thesis?
Nailing one's doctoral thesis by simply nailing it up for viewing is an old tradition that possibly dates back to Martin Luther. The tradition has lost its former glory but is stil...
Neuroimmune crosstalk in early Alzheimer’s disease – PhD interview with Megg Garcia-Ryde
Megg Garcia-Ryde’s thesis sheds light on the early pathological processes in Alzheimer’s disease and the interplay between neurons and microglia as the disease evolves. October 10,...
CoPARLU –Centre of Physical Activity Research at Lund University
Collaboration is the most efficient way of moving science forward. That is why our research group initiated a network inviting all researchers interested in physical activity inves...
Why research replication fails
Communication is key in research. Recently, our lab had a team-building day at the beach. And a simple Lego game can tell very much about the reasons behind the reproducibility cri...